Metabolic engineering of yeasts for green and sustainable production of bioactive ginsenosides F2 and 3β,20S-Di-O-Glc-DM

• Main Authors: Fenglin Jiang (Author), Chen Zhou (Author), Yan Li (Author), Haidong Deng (Author), Ting Gong (Author), Jingjing Chen (Author), Tianjiao Chen (Author), Jinling Yang (Author), Ping Zhu (Author)
• Format: Book
• Published: Elsevier, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Both natural ginsenoside F2 and unnatural ginsenoside 3β,20S-Di-O-Glc-DM were reported to exhibit anti-tumor activity. Traditional approaches for producing them rely on direct extraction from Panax ginseng, enzymatic catalysis or chemical synthesis, all of which result in low yield and high cost. Me...