MPASL: multi-perspective learning knowledge graph attention network for synthetic lethality prediction in human cancer

• Main Authors: Ge Zhang (Author), Yitong Chen (Author), Chaokun Yan (Author), Jianlin Wang (Author), Wenjuan Liang (Author), Junwei Luo (Author), Huimin Luo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Synthetic lethality (SL) is widely used to discover the anti-cancer drug targets. However, the identification of SL interactions through wet experiments is costly and inefficient. Hence, the development of efficient and high-accuracy computational methods for SL interactions prediction is of great s...