Presence of antigen-experienced T cells with low grade of differentiation and proliferative potential in chronic Chagas disease myocarditis.

• Главные авторы: Rafael J Argüello (Автор), Carlos Vigliano (Автор), Patricia Cabeza-Meckert (Автор), Rodolfo Viotti (Автор), Fernando Garelli (Автор), Liliana E Favaloro (Автор), Roberto R Favaloro (Автор), Rubén Laguens (Автор), Susana A Laucella (Автор)
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• Опубликовано: Public Library of Science (PLoS), 2014-08-01T00:00:00Z.
• Предметы: article
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The main consequence of chronic Trypanosoma cruzi infection is the development of myocarditis in approximately 20-30% of infected individuals but not until 10-20 years after the initial infection. We have previously shown that circulating interferon-γ-secreting T cells responsive to Trypanosoma cruz...