MicroRNA199a-Based Post-transcriptional Detargeting of Gene Vectors for Hepatocellular Carcinoma

• Váldodahkkit: Bijay Dhungel (Dahkki), Charmaine A. Ramlogan-Steel (Dahkki), Christopher J. Layton (Dahkki), Jason C. Steel (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2018-12-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

A gene therapeutic platform needs to be both efficient and safe. The criterion of safety is particularly important for diseases like hepatocellular carcinoma (HCC), which develop in a background of an already compromised liver. Gene vectors can be constructed either by targeting HCC or by detargetin...