Protein Kinase G Is Involved in Acute but Not in Long-Term Regulation of Renin Secretion

• Main Authors: Andrea Schramm (Author), Frank Schweda (Author), Maria Luisa S. Sequeira-Lopez (Author), Franz Hofmann (Author), Peter Sandner (Author), Jens Schlossmann (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pharmacological inhibition of the renin-angiotensin-aldosterone system (RAAS) is, in combination with diuretics, the first-choice treatment for hypertension, although 10-20% of patients do not respond adequately. Next to the RAAS, the nitric oxide/cGMP/protein kinase G (PKG) system is the second fun...