An in vitro model of human neocortical development using pluripotent stem cells: cocaine-induced cytoarchitectural alterations

• Main Authors: Abigail A. Kindberg (Author), Raphael M. Bendriem (Author), Charles E. Spivak (Author), Jia Chen (Author), Annelie Handreck (Author), Carl R. Lupica (Author), Jinny Liu (Author), William J. Freed (Author), Chun-Ting Lee (Author)
• Format: Book
• Published: The Company of Biologists, 2014-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neocortical development involves ordered specification of forebrain cortical progenitors to various neuronal subtypes, ultimately forming the layered cortical structure. Modeling of this process using human pluripotent stem cells (hPSCs) would enable mechanistic studies of human neocortical developm...