In Vitro Effects of VA441, a New Selective Cyclooxygenase-2 Inhibitor, on Human Osteoarthritic Chondrocytes exposed to IL-1β

• Main Authors: Antonella Fioravanti (Author), Laura Tinti (Author), Nicola Antonio Pascarelli (Author), Angela Di Capua (Author), Antonello Lamboglia (Author), Andrea Cappelli (Author), Mariangela Biava (Author), Antonio Giordani (Author), Silvia Niccolini (Author), Mauro Galeazzi (Author), Maurizio Anzini (Author)
• Format: Book
• Published: Elsevier, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this in vitro study was to examine the possible effect of [2-methyl-5-(4-methylsulphonyl)phenyl-1-phenyl-3-(2-n-propyloxyethyl)]-1H-pyrrole (VA441), a new selective cyclooxygenase (COX)-2 inhibitor, on human osteoarthritic (OA) chondrocyte cultivated in the presence or absence of interleu...