Dexamethasone Provides Effective Immunosuppression for Improved Survival of Retinal Organoids after Epiretinal Transplantation

• Main Authors: Bikun Xian (Author), Ziming Luo (Author), Kaijing Li (Author), Kang Li (Author), Mingjun Tang (Author), Runcai Yang (Author), Shoutao Lu (Author), Haijun Zhang (Author), Jian Ge (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We investigated the efficacy of the immunosuppressants rapamycin (RAP) and dexamethasone (DEX) in improving the survival of retinal organoids after epiretinal transplantation. We first compared the immunosuppressive abilities of DEX and RAP in activated microglia in an in vitro setting. Following th...