Transcriptional analysis of THP-1 cells infected with Leishmania infantum indicates no activation of the inflammasome platform.

• Main Authors: Mariana Gatto (Author), Patrícia Aparecida Borim (Author), Ivan Rodrigo Wolf (Author), Taís Fukuta da Cruz (Author), Gustavo Augusto Ferreira Mota (Author), Aline Márcia Marques Braz (Author), Bárbara Casella Amorim (Author), Guilherme Targino Valente (Author), Marjorie de Assis Golim (Author), James Venturini (Author), João Pessoa Araújo Junior (Author), Alessandra Pontillo (Author), Alexandrina Sartori (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leishmaniasis is caused by intracellular parasites transmitted to vertebrates by sandfly bites. Clinical manifestations include cutaneous, mucosal or visceral involvement depending upon the host immune response and the parasite species. To assure their survival inside macrophages, these parasites de...