Dihydromyricetin Attenuates Diabetic Cardiomyopathy by Inhibiting Oxidative Stress, Inflammation and Necroptosis via Sirtuin 3 Activation

• Main Authors: Yun Chen (Author), Yangyang Zheng (Author), Ruixiang Chen (Author), Jieru Shen (Author), Shuping Zhang (Author), Yunhui Gu (Author), Jiahai Shi (Author), Guoliang Meng (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dihydromyricetin (DHY), the main flavonoid component in <i>Ampelopsis grossedentata</i>, has important benefits for health. The present study aimed to investigate the exact effects and possible mechanisms of DHY on diabetic cardiomyopathy (DCM). Male C57BL/6 mice and sirtuin 3 (SIRT3) kn...