Dihydromyricetin Attenuates Diabetic Cardiomyopathy by Inhibiting Oxidative Stress, Inflammation and Necroptosis via Sirtuin 3 Activation

• Glavni autori: Yun Chen (Autor), Yangyang Zheng (Autor), Ruixiang Chen (Autor), Jieru Shen (Autor), Shuping Zhang (Autor), Yunhui Gu (Autor), Jiahai Shi (Autor), Guoliang Meng (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2023-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Dihydromyricetin (DHY), the main flavonoid component in <i>Ampelopsis grossedentata</i>, has important benefits for health. The present study aimed to investigate the exact effects and possible mechanisms of DHY on diabetic cardiomyopathy (DCM). Male C57BL/6 mice and sirtuin 3 (SIRT3) kn...