Pathophysiological Mechanisms and Potential Therapeutic Targets in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL)

• Main Authors: Martina Locatelli (Author), Alessandro Padovani (Author), Alessandro Pezzini (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), is a hereditary small-vessels angiopathy caused by mutations in the NOTCH 3 gene, located on chromosome 19, usually affecting middle-ages adults, whose clinical manifestations include migraine with...