A Simple Computational Tool for Accurate, Quantitative Prediction of One-Electron Reduction Potentials of Hypoxia-Activated Tirapazamine Analogues
The reduction potentials of bioreductively-activated drugs represent an important design parameter to be accommodated in the course of creating lead compounds and improving the efficacy of older generation drugs. Reduction potentials are traditionally reported as single-electron reduction potential...
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| Main Authors: | , , |
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| Format: | Book |
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Frontiers Media S.A.,
2020-06-01T00:00:00Z.
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A1234.567 |
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