Genomic trajectory in leukemogenesis of myeloproliferative neoplasms: a case report

• Autors principals: Yujie Chen (Autor), Rafee Talukder (Autor), Brian Y. Merritt (Autor), Katherine Y. King (Autor), Marek Kimmel (Autor), Gustavo Rivero (Autor), Romina Sosa (Autor)
• Format: Llibre
• Publicat: BMC, 2021-05-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract Background We report a patient with Essential Thrombocythemia (ET), subsequently diagnosed with concurrent myeloid and lymphoid leukemia. Generally, the molecular mechanisms underlying leukemic transformation of Philadelphia-negative myeloproliferative neoplasms (Ph-MPN) are poorly understo...