Exposure of Mesenchymal Stem Cells to an Alzheimer's Disease Environment Enhances Therapeutic Effects

• Egile Nagusiak: Sang Eon Park (Egilea), Hyeong Seop Kim (Egilea), Soo Jin Kwon (Egilea), Min-Jeong Kim (Egilea), Suk-joo Choi (Egilea), Soo-young Oh (Egilea), Gyu Ha Ryu (Egilea), Hong Bae Jeon (Egilea), Duk L. Na (Egilea), Jong Wook Chang (Egilea)
• Formatua: Liburua
• Argitaratua: Hindawi Limited, 2021-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Mesenchymal stem cells (MSCs) have emerged as a promising tool for the treatment of Alzheimer's disease (AD). Previous studies suggested that the coculture of human MSCs with AD in an in vitro model reduced the expression of amyloid-beta 42 (Aβ42) in the medium as well as the overexpression of...