Exposure of Mesenchymal Stem Cells to an Alzheimer's Disease Environment Enhances Therapeutic Effects

• Main Authors: Sang Eon Park (Author), Hyeong Seop Kim (Author), Soo Jin Kwon (Author), Min-Jeong Kim (Author), Suk-joo Choi (Author), Soo-young Oh (Author), Gyu Ha Ryu (Author), Hong Bae Jeon (Author), Duk L. Na (Author), Jong Wook Chang (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mesenchymal stem cells (MSCs) have emerged as a promising tool for the treatment of Alzheimer's disease (AD). Previous studies suggested that the coculture of human MSCs with AD in an in vitro model reduced the expression of amyloid-beta 42 (Aβ42) in the medium as well as the overexpression of...