In Silico Mapping of Essential Residues in the Catalytic Domain of PDE5 Responsible for Stabilization of Its Commercial Inhibitors
Phosphodiesterase type 5 (PDE5) is an important enzyme associated with the hydrolysis of cyclic guanosine monophosphate (cGMP) to guanosine monophosphate (GMP). Due to the relevant role of second messenger cGMP as a mediator in many physiological processes, efforts have been converged to find a safe...
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| Main Authors: | , , |
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| Format: | Book |
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MDPI AG,
2019-11-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |