Ouabain Modulates Zymosan-Induced Peritonitis in Mice

• Main Authors: Jacqueline Alves Leite (Author), Anne Kaliery De Abreu Alves (Author), José Guilherme Marques Galvão (Author), Mariana Pires Teixeira (Author), Luiz Henrique Agra Cavalcante-Silva (Author), Cristoforo Scavone (Author), Alexandre Morrot (Author), Vivian Mary Rumjanek (Author), Sandra Rodrigues-Mascarenhas (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ouabain, a potent inhibitor of the Na+, K+-ATPase, was identified as an endogenous substance. Recently, ouabain was shown to affect various immunological processes. We have previously demonstrated the ability of ouabain to modulate inflammation, but little is known about the mechanisms involved. Thu...