Arctigenin Attenuates Tumor Metastasis Through Inhibiting Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma via Suppressing GSK3β-Dependent Wnt/β-Catenin Signaling Pathway In Vivo and In Vitro

• المؤلفون الرئيسيون: Zheng Lu (مؤلف), Lingling Chang (مؤلف), Hongbo Zhou (مؤلف), Xiaoqiang Liu (مؤلف), Yinqian Li (مؤلف), Tiejun Mi (مؤلف), Dewen Tong (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Arctigenin (ARG) has been reported to be a bioactive lignan from Arctium lappa exerting various activities including anti-cancer and immune-regulation. The present study aimed to investigate the anti-metastasis activity and mechanism of ARG against hepatocellular carcinoma in vitro and in vivo. The...