Synthesis, Neuroprotective Effect and Physicochemical Studies of Novel Peptide and Nootropic Analogues of Alzheimer Disease Drug

• Main Authors: Radoslav Chayrov (Author), Tatyana Volkova (Author), German Perlovich (Author), Li Zeng (Author), Zhuorong Li (Author), Martin Štícha (Author), Rui Liu (Author), Ivanka Stankova (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glutamate is an excitatory neurotransmitter in the nervous system. Excessive glutamate transmission can lead to increased calcium ion expression, related to increased neurotoxicity. Memantine is used for treating patients with Alzheimer's disease (AD) due to its protective action on the neurons...