Physical Properties and Effect in a Battery of Safety Pharmacology Models for Three Structurally Distinct Enteric Polymers Employed as Spray-dried Dispersion Carriers

• Main Authors: Ryan M Fryer (Author), Mita Patel (Author), Xiaomei Zhang (Author), Katja S Baum-Kroker (Author), Akalushi Muthukumarana (Author), Brian Linehan (Author), Yin-Chao Tseng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Establishing a wide therapeutic index (TI) for pre-clinical safety is important during lead optimization (LO) in research, prior to clinical development, although is often limited by a molecules physiochemical characteristics. Recent advances in the application of the innovative vibrating mesh spray...