Modified PEG-Lipids Enhance the Nasal Mucosal Immune Capacity of Lipid Nanoparticle mRNA Vaccines

• Main Authors: Meng Li (Author), Jing Yi (Author), Yicheng Lu (Author), Ting Liu (Author), Haonan Xing (Author), Xiwei Wang (Author), Hui Zhang (Author), Nan Liu (Author), Zengming Wang (Author), Aiping Zheng (Author)
• Format: Book
• Published: MDPI AG, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Objectives: Omicron, the predominant variant of SARS-CoV-2, exhibits strong immune-evasive properties, leading to the reduced efficacy of existing vaccines. Consequently, the development of versatile vaccines is imperative. Intranasal mRNA vaccines offer convenient administration and have...