Characterization and antitumor efficacy of poly(L-lactid acid)-based etoposide-loaded implants

• Main Authors: Li Gao (Author), Chuanqi Xie (Author), Yuzhi Du (Author), Xiaodong Wang (Author), Erkang Xuan (Author), Xiuxiu Liu (Author), Yang Zhao (Author), Jianjian Xu (Author), Lan Luo (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Etoposide is widely used in the chemotherapy of a variety of malignancies. But the strong lipophilicity, poor bioavailability, and severe side effects of etoposide limit its clinical application. The aim of this study was to develop sustained-release etoposide-loaded implants and evaluate antitumor...