ATP Is Required and Advances Cytokine-Induced Gap Junction Formation in Microglia In Vitro

• Main Authors: Pablo J. Sáez (Author), Kenji F. Shoji (Author), Mauricio A. Retamal (Author), Paloma A. Harcha (Author), Gigliola Ramírez (Author), Jean X. Jiang (Author), Rommy von Bernhardi (Author), Juan C. Sáez (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Microglia are the immune cells in the central nervous system. After injury microglia release bioactive molecules, including cytokines and ATP, which modify the functional state of hemichannels (HCs) and gap junction channels (GJCs), affecting the intercellular communication via extracellular and int...