The Fungal Metabolite (+)-Terrein Abrogates Ovariectomy-Induced Bone Loss and Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastogenesis by Suppressing Protein Kinase-C α/βII Phosphorylation

• Main Authors: Kyosuke Sakaida (Author), Kazuhiro Omori (Author), Masaaki Nakayama (Author), Hiroki Mandai (Author), Saki Nakagawa (Author), Hidefumi Sako (Author), Chiaki Kamei (Author), Satoshi Yamamoto (Author), Hiroya Kobayashi (Author), Satoki Ishii (Author), Mitsuaki Ono (Author), Soichiro Ibaragi (Author), Keisuke Yamashiro (Author), Tadashi Yamamoto (Author), Seiji Suga (Author), Shogo Takashiba (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoporosis is a common disease characterized by a systemic impairment of bone mass and microarchitecture that results in fragility fractures. Severe bone loss due to osteoporosis triggers pathological fractures and consequently decreases the daily life activity and quality of life. Therefore, prev...