Understanding Human Cerebral Malaria through a Blood Transcriptomic Signature: Evidences for Erythrocyte Alteration, Immune/Inflammatory Dysregulation, and Brain Dysfunction

• Main Authors: Sandrine Cabantous (Author), Belco Poudiougou (Author), Aurélie Bergon (Author), Abdoulaye Barry (Author), Aboubacar A. Oumar (Author), Abdoulaye M. Traore (Author), Christophe Chevillard (Author), Ogobara Doumbo (Author), Alain Dessein (Author), Sandrine Marquet (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Cerebral malaria (CM), a reversible encephalopathy affecting young children, is a medical emergency requiring rapid clinical assessment and treatment. However, understanding of the genes/proteins and the biological pathways involved in the disease outcome is still limited. Methods. We ha...