Association of the hypoxia-inducible factor-1α (HIF-1α) gene polymorphisms with prognosis in ovarian clear cell carcinoma

• Main Authors: Hiroyuki Suzuki (Author), Mitsutake Yano (Author), Mariko Miyazawa (Author), Masaki Miyazawa (Author), Naoki Ogane (Author), Kosei Hasegawa (Author), Hitoshi Tsuda (Author), Masayuki Yoshida (Author), Ryugo Okagaki (Author), Osamu Ishihara (Author), Masanori Yasuda (Author)
• Format: Book
• Published: BMC, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Ovarian clear cell carcinoma (OCCC) is the second most common ovarian cancer after serous carcinoma in Japan. OCCC has a more unfavorable clinical outcome due to a poor response to platinum-based chemotherapy, compared with serous carcinoma. Hypoxia inducible factor-1α (HIF-1α) i...