Virtual screening to identify pathogenic functional mutations in the exon of ACTN3 gene, which codes for masseter muscle, thereby affecting mandibular morphology

• Main Authors: Vijayashree Priyadharsini Jayaseelan (Author), Ashwin Mathew George (Author), A Sumathi Felicita (Author), Paramasivam Arumugam (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: To determine if In silico methods can be used to identify pathogenic non-synonymous variants in the ACTN3 (alpha actinin 3) alpha actinin gene that encodes for alpha actinin 3 three protein employing computational tools. Materials and Methods: In silico methods of detecting pathogenic variants...