Evaluation of agonist and antagonist radioligands for somatostatin receptor imaging of breast cancer using positron emission tomography

• 主要な著者: Iulia Dude (著者), Zhengxing Zhang (著者), Julie Rousseau (著者), Navjit Hundal-Jabal (著者), Nadine Colpo (著者), Helen Merkens (著者), Kuo-Shyan Lin (著者), François Bénard (著者)
• フォーマット: 図書
• 出版事項: SpringerOpen, 2017-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background The somatostatin receptor subtype 2 (sstr2) is expressed on a majority of luminal breast cancers, however SPECT and scintigraphy imaging with agonistic sstr2 probes has been sub-optimal. High affinity antagonists can access more binding sites on the cell surface, resulting in hig...