MMP24 Contributes to Neuropathic Pain in an FTO-Dependent Manner in the Spinal Cord Neurons

• Main Authors: Longfei Ma (Author), Yangyuxin Huang (Author), Fengjiang Zhang (Author), Dave Schwinn Gao (Author), Na Sun (Author), Jinxuan Ren (Author), Suyun Xia (Author), Jia Li (Author), Xinyi Peng (Author), Lina Yu (Author), Bao-Chun Jiang (Author), Min Yan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nerve injury-induced gene expression change in the spinal cord is critical for neuropathic pain genesis. RNA N6-methyladenosine (m6A) modification represents an additional layer of gene regulation. We showed that spinal nerve ligation (SNL) upregulated the expression of matrix metallopeptidase 24 (M...