Terbium-Based AGuIX-Design Nanoparticle to Mediate X-ray-Induced Photodynamic Therapy

• Main Authors: Joël Daouk (Author), Mathilde Iltis (Author), Batoul Dhaini (Author), Denise Béchet (Author), Philippe Arnoux (Author), Paul Rocchi (Author), Alain Delconte (Author), Benoît Habermeyer (Author), François Lux (Author), Céline Frochot (Author), Olivier Tillement (Author), Muriel Barberi-Heyob (Author), Hervé Schohn (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

X-ray-induced photodynamic therapy is based on the energy transfer from a nanoscintillator to a photosensitizer molecule, whose activation leads to singlet oxygen and radical species generation, triggering cancer cells to cell death. Herein, we synthesized ultra-small nanoparticle chelated with Terb...