Exploring the Involvement of NLRP3 and IL-1β in Osteoarthritis of the Hand: Results from a Pilot Study

• Main Authors: Antonella Fioravanti (Author), Sara Tenti (Author), Megan McAllister (Author), Melody Chemaly (Author), Amanda Eakin (Author), Joseph McLaughlin (Author), Anthony J. Bjourson (Author), Elena Frati (Author), Victoria McGilligan (Author), Sara Cheleschi (Author), David S. Gibson (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hand osteoarthritis (HOA) includes different subsets; a particular and uncommon form is erosive HOA (EHOA). Interleukin- (IL-) 1β plays a crucial role in the pathogenesis of osteoarthritis (OA); it is synthesized as an inactive precursor which requires the intervention of a cytosolic multiprotein co...