Evaluation of ctDNA in the Prediction of Response to Neoadjuvant Therapy and Prognosis in Locally Advanced Rectal Cancer Patients: A Prospective Study

• Main Authors: Marina Morais (Author), Telma Fonseca (Author), Diogo Melo-Pinto (Author), Isabel Prieto (Author), Ana Teresa Vilares (Author), Ana Luísa Duarte (Author), Patrícia Leitão (Author), Luís Cirnes (Author), José Carlos Machado (Author), Silvestre Carneiro (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

"Watch and wait" is becoming a common treatment option for patients with locally advanced rectal cancer (LARC) submitted to neoadjuvant treatment. However, currently, no clinical modality has an acceptable accuracy for predicting pathological complete response (pCR). The aim of this study...