Preclinical assessment of IRDye800CW‐labeled gastrin‐releasing peptide receptor‐targeting peptide for near infrared‐II imaging of brain malignancies

• Main Authors: Yuan Zhang (Author), Li Wang (Author), Chengkai Zhang (Author), Jingjing Zhang (Author), Linhao Yuan (Author), Shucheng Jin (Author), Wenjianlong Zhou (Author), Xiudong Guan (Author), Peng Kang (Author), Chuanbao Zhang (Author), Jie Tian (Author), Xiaoyuan Chen (Author), Deling Li (Author), Wang Jia (Author)
• Format: Book
• Published: Wiley, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract We aimed to develop a new biocompatible gastrin‐releasing peptide receptor (GRPR) targeted optical probe, IRDye800‐RM26, for fluorescence image‐guided surgery (FGS) of brain malignancies in near‐infrared window II (NIR‐II) imaging. We developed a novel GRPR targeting probe using a nine‐amin...