Targeting Platelet Thrombin Receptor Signaling to Prevent Thrombosis

• Główni autorzy: Susan S. Smyth (Autor), Eric L. Wallace (Autor)
• Format: Książka
• Wydane: MDPI AG, 2013-08-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Platelets contribute fundamentally to ischemic heart disease, and antiplatelet therapy has been critical to reducing acute thrombotic complications of atherosclerotic disease. Thrombin, by acting on protease activated receptors (PAR), is one of the most potent platelet activators. PAR-1 antagonists...