Effect of packed red blood cell transfusion on IL-8 and sICAM-1 in premature neonates at different postnatal ages

• Main Authors: Lamiaa Mohsen (Author), Hala Youssef (Author), Hala Abdelrahman (Author), Rabab El Hawary (Author), Abeer Selim (Author), Safwat Aly (Author), Mustafa Nada (Author), Hany Aly (Author)
• Format: Book
• Published: Elsevier, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Transfusion-related immunomodulation (TRIM) has been described in adults; however, its existence in neonates is not confirmed. The generation of TRIM is attributed to increased concentrations of IL-8, sICAM-1 and other pro-inflammatory cytokines. This study aimed to monitor changes in IL...