SuperGAG biopolymers for treatment of excessive bladder permeability

• Main Authors: Rheal A. Towner (Author), Beverley Greenwood‐Van Meerveld (Author), Ehsan Mohammadi (Author), Debra Saunders (Author), Nataliya Smith (Author), Grannum R. Sant (Author), Harrison C. Shain (Author), Thomas H. Jozefiak (Author), Robert E. Hurst (Author)
• Format: Book
• Published: Wiley, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Few therapeutic options exist for treatment of IC/BPS. A novel high MW GAG biopolymer ("SuperGAG") was synthesized by controlled oligomerization of CS, purified by TFF and characterized by SEC‐MALLS and 1H‐NMR spectroscopy. The modified GAG biopolymer was tested in an OVX female r...