Dinuclear Iron Complexes of Iminopyridine-Based Ligands as Selective Cytotoxins for Tumor Cells and Inhibitors of Cancer Cell Migration

• Main Authors: Jessica Castro (Author), Marlon Bravo (Author), Meritxell Albertí (Author), Anaís Marsal (Author), María José Alonso-De Gennaro (Author), Oriol Martínez-Ferraté (Author), Carmen Claver (Author), Piet W. N. M. van Leeuwen (Author), Isabel Romero (Author), Antoni Benito (Author), Maria Vilanova (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A family of dinuclear iron (II) compounds with iminopyridine-based ligands displays selective cytotoxic activity against cancer cell lines. All compounds have IC₅₀ values 2-6 fold lower than that of cisplatin, and 30-90 fold lower than that of carboplatin for the tumor cell li...