Dinuclear Iron Complexes of Iminopyridine-Based Ligands as Selective Cytotoxins for Tumor Cells and Inhibitors of Cancer Cell Migration

• Главные авторы: Jessica Castro (Автор), Marlon Bravo (Автор), Meritxell Albertí (Автор), Anaís Marsal (Автор), María José Alonso-De Gennaro (Автор), Oriol Martínez-Ferraté (Автор), Carmen Claver (Автор), Piet W. N. M. van Leeuwen (Автор), Isabel Romero (Автор), Antoni Benito (Автор), Maria Vilanova (Автор)
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• Опубликовано: MDPI AG, 2022-12-01T00:00:00Z.
• Предметы: article
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A family of dinuclear iron (II) compounds with iminopyridine-based ligands displays selective cytotoxic activity against cancer cell lines. All compounds have IC₅₀ values 2-6 fold lower than that of cisplatin, and 30-90 fold lower than that of carboplatin for the tumor cell li...