Topical Delivery of Diacetyl Boldine in a Microemulsion Formulation for Chemoprotection against Melanoma

• Main Authors: Ahmed Al Saqr (Author), Manjusha Annaji (Author), Ishwor Poudel (Author), Mohammed F. Aldawsari (Author), Hamad Alrbyawi (Author), Nur Mita (Author), Muralikrishnan Dhanasekaran (Author), Sai H. S. Boddu (Author), Rabin Neupane (Author), Amit K. Tiwari (Author), R. Jayachandra Babu (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to develop a microemulsion formulation for topical delivery of Diacetyl Boldine (DAB) and to evaluate its cytotoxicity against melanoma cell line (B16BL6) in vitro. Using a pseudo-ternary phase diagram, the optimal microemulsion formulation region was identified, and its particle si...