Structural optimization and de novo design of dengue virus entry inhibitory peptides.
Viral fusogenic envelope proteins are important targets for the development of inhibitors of viral entry. We report an approach for the computational design of peptide inhibitors of the dengue 2 virus (DENV-2) envelope (E) protein using high-resolution structural data from a pre-entry dimeric form o...
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| Principais autores: | , , , , , , , , , , |
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| Formato: | Livro |
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Public Library of Science (PLoS),
2010-06-01T00:00:00Z.
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