Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer

• المؤلفون الرئيسيون: Peter A. Halim (مؤلف), Rasha A. Hassan (مؤلف), Khaled O. Mohamed (مؤلف), Soha O. Hassanin (مؤلف), Mona G. Khalil (مؤلف), Amr M. Abdou (مؤلف), Eman O. Osman (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2022-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Novel halogenated phenoxychalcones 2a-f and their corresponding N-acetylpyrazolines 3a-f were synthesised and evaluated for their anticancer activities against breast cancer cell line (MCF-7) and normal breast cell line (MCF-10a), compared with staurosporine. All compounds showed moderate to good cy...