GPX8+ cancer-associated fibroblast, as a cancer-promoting factor in lung adenocarcinoma, is related to the immunosuppressive microenvironment

• Main Authors: Ying Bai (Author), Tao Han (Author), Yunjia Dong (Author), Chao Liang (Author), Lu Gao (Author), Yafeng Liu (Author), Jiawei Zhou (Author), Jianqiang Guo (Author), Deyong Ge (Author), Jing Wu (Author), Dong Hu (Author)
• Format: Book
• Published: BMC, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cancer-associated fibroblasts (CAFs) play a crucial role in the tumor microenvironment of lung adenocarcinoma (LUAD) and are often associated with poorer clinical outcomes. This study aimed to screen for CAF-specific genes that could serve as promising therapeutic targets for LUA...