Matrine counteracts obesity in mice via inducing adipose thermogenesis by activating HSF1/PGC-1α axis

• Main Authors: Chan Li (Author), Yao-Hao Xu (Author), Yu-Tao Hu (Author), Xiu Zhou (Author), Zhi-Shu Huang (Author), Ji-Ming Ye (Author), Yong Rao (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Promoting energy expenditure is known to curb obesity and can be exploited for its treatment. Our previous study has demonstrated that activation of HSF1/PGC-1α axis efficiently induced mitochondrial biogenesis and adaptive oxidation and thus ameliorating lipid accumulation, however, whether it can...