Next Generation PDE4 Inhibitors that Selectively Target PDE4B/D Subtypes: A Narrative Review

• Egile Nagusiak: Andrew Blauvelt (Egilea), Richard G. Langley (Egilea), Kenneth B. Gordon (Egilea), Jonathan I. Silverberg (Egilea), Kilian Eyerich (Egilea), Morten O. A. Sommer (Egilea), Jakob Felding (Egilea), Richard B. Warren (Egilea)
• Formatua: Liburua
• Argitaratua: Adis, Springer Healthcare, 2023-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract For decades, topical corticosteroids have been the mainstay of treatment for mild-to-moderate inflammatory skin diseases, even though only short-term use is approved for these agents and systemic inflammation is not addressed. Increased understanding of the immunopathogenesis of these condi...