Prospective study to characterize adalimumab exposure in pediatric patients with rheumatic diseases

• Main Authors: Tatjana Welzel (Author), Klervi Golhen (Author), Andrew Atkinson (Author), Verena Gotta (Author), David Ternant (Author), Jasmin B. Kuemmerle-Deschner (Author), Christine Michler (Author), Gilbert Koch (Author), Johannes N. van den Anker (Author), Marc Pfister (Author), Andreas Woerner (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background In pediatric rheumatic diseases (PRD), adalimumab is dosed using fixed weight-based bands irrespective of methotrexate co-treatment, disease activity (DA) or other factors that might influence adalimumab pharmacokinetics (PK). In rheumatoid arthritis (RA) adalimumab exposure betw...