Synthesis and biological evaluation of novel N9-heterobivalent β-carbolines as angiogenesis inhibitors

A series of novel N9-heterobivalent β-carbolines has been synthesized. All the novel compounds were tested for their anticancer activity against six tumour cell lines in vitro. Among these molecules, compounds 5b, and 5w exhibited strong cytotoxic activities with IC50 value of lower than 20 μM. Acut...

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Bibliographic Details
Main Authors: Liang Guo (Author), Qin Ma (Author), Wei Chen (Author), Wenxi Fan (Author), Jie Zhang (Author), Bin Dai (Author)
Format: Book
Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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