C₆₀ Fullerene as an Effective Nanoplatform of Alkaloid Berberine Delivery into Leukemic Cells

• Main Authors: Anna Grebinyk (Author), Svitlana Prylutska (Author), Anatoliy Buchelnikov (Author), Nina Tverdokhleb (Author), Sergii Grebinyk (Author), Maxim Evstigneev (Author), Olga Matyshevska (Author), Vsevolod Cherepanov (Author), Yuriy Prylutskyy (Author), Valeriy Yashchuk (Author), Anton Naumovets (Author), Uwe Ritter (Author), Thomas Dandekar (Author), Marcus Frohme (Author)
• Format: Book
• Published: MDPI AG, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A herbal alkaloid Berberine (Ber), used for centuries in Ayurvedic, Chinese, Middle-Eastern, and native American folk medicines, is nowadays proved to function as a safe anticancer agent. Yet, its poor water solubility, stability, and bioavailability hinder clinical application. In this study, we ha...