Assessment and prediction of tablet properties using transmission and backscattering Raman spectroscopy and transmission NIR spectroscopy

• Main Authors: Elisabeth Peeters (Author), Ana Filipa Tavares da Silva (Author), Maunu Toiviainen (Author), Jeroen Van Renterghem (Author), Jurgen Vercruysse (Author), Mikko Juuti (Author), Joao Almeida Lopes (Author), Thomas De Beer (Author), Chris Vervaet (Author), Jean-Paul Remon (Author)
• Format: Book
• Published: Elsevier, 2016-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study investigated whether Raman and Near Infrared (NIR) spectroscopy could predict tablet properties. Granules were produced on a continuous line by varying granulation parameters. Tableting process parameters were adjusted to obtain uniform tablet weight and thickness. Spectra were collected...