Dual-targeting cyclic peptides of receptor-binding domain (RBD) and main protease (Mpro) as potential drug leads for the treatment of SARS-CoV-2 infection

• Główni autorzy: Zhen Xu (Autor), Yunting Zou (Autor), Xi Gao (Autor), Miao-Miao Niu (Autor), Jindong Li (Autor), Lu Xue (Autor), Su Jiang (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The receptor-binding domain (RBD) and the main protease (Mpro) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) play a crucial role in the entry and replication of viral particles, and co-targeting both of them could be an attractive approach for the treatment of SARS-CoV-2 infection...