The malnutrition-related increase in early visceralization of Leishmania donovani is associated with a reduced number of lymph node phagocytes and altered conduit system flow.

• Asıl Yazarlar: Marwa K Ibrahim (Yazar), Jeffrey L Barnes (Yazar), Gregory M Anstead (Yazar), Fabio Jimenez (Yazar), Bruno L Travi (Yazar), Alex G Peniche (Yazar), E Yaneth Osorio (Yazar), Seema S Ahuja (Yazar), Peter C Melby (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

In a murine model of moderate childhood malnutrition we found that polynutrient deficiency led to a 4-5-fold increase in early visceralization of L. donovani (3 days post-infection) following cutaneous infection and a 16-fold decrease in lymph node barrier function (p<0.04 for all). To begin to u...