Physiologically based pharmacokinetic modeling of candesartan to predict the exposure in hepatic and renal impairment and elderly populations

Background: Candesartan cilexetil is a widely used angiotensin II receptor blocker with minimal adverse effects and high tolerability for the treatment of hypertension. Candesartan is administered orally as the prodrug candesartan cilexetil, which is wholly and swiftly converted to the active metabo...

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Main Authors: Lingfeng Guo (Author), Xinyu Zhu (Author), Lei Zhang (Author), Yichao Xu (Author)
Format: Book
Published: SAGE Publishing, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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