Inherited Thrombocytopenia Caused by Germline Mutation Should Be Considered in Young Patients With Suspected Myelodysplastic Syndrome

• मुख्य लेखकों: Tariq Kewan (लेखक), Ryan Noss (लेखक), Lucy A. Godley (लेखक), Heesun J. Rogers (लेखक), Hetty E. Carraway (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: SAGE Publishing, 2020-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Thrombocytopenia 2 (THC2) is an autosomal dominant disorder characterized by ankyrin repeat domain 26 mutation and moderate thrombocytopenia. THC2 exposes patients to a low risk of bleeding and an increased likelihood of myelodysplastic syndrome/acute myeloid leukemia. Germline evaluation for a gene...